Jay Leno will welcome Jay-Z who will perform with Rihanna and Kanye West when the trio of entertainers break the seal on Leno’s new series in the premiere of "The Jay Leno Show" (Monday-Friday, 10-11 p.m. ET) as the new comedy series debuts on Monday, September 14.

Jay-Z with Rihanna and West will be the first to rock the program’s brand new stage as they perform "Run This Town." The song is from Jay-Z’s highly anticipated new album "The Blueprint 3," which will be available in stores and online on September 11.

"The Jay Leno Show" will be the first-ever entertainment program to be stripped across primetime on broadcast network television and will showcase many of the features that have made Leno America’s late-night leader for more than a dozen years.

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